Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation
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چکیده
منابع مشابه
Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.
AIMS Anti-platelet agents, such as dipyridamole, have several clinical benefits for peripheral artery disease with the speculation of angiogenic potential that could preserve ischaemic tissue viability, yet the effect of dipyridamole on ischaemic arteriogenesis or angiogenesis is unknown. Here we test the hypothesis that dipyridamole therapy augments arteriolar vessel development and function d...
متن کاملDoes dipyridamole-induced ischaemia affect NT-proBNP secretion?
BACKGROUND B-type natriuretic peptide (BNP) and the inactive amino-terminal pro-B-type natriuretic peptide (NTproBNP) have a prognostic value in heart failure and in myocardial infarction. There has been some evidence that BNP and NT-proBNP can be used in the diagnosis of myocardial ischaemia by improving the sensitivity of exercise- stress testing. OBJECTIVE To observe the relationship betwe...
متن کاملCardiovascular Topics Does dipyridamole-induced ischaemia affect NT-proBNP secretion?
Background: B-type natriuretic peptide (BNP) and the inactive amino-terminal pro-B-type natriuretic peptide (NTproBNP) have a prognostic value in heart failure and in myocardial infarction. There has been some evidence that BNP and NT-proBNP can be used in the diagnosis of myocardial ischaemia by improving the sensitivity of exercise-stress testing. Objective: To observe the relationship betwee...
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Arginine vasopressin (AVP) plays a key role in the urine concentration mechanism via the vasopressin V2 receptor (V2R) and aquaporin 2 (AQP2) in the kidney. It is well known that V2R is localized on the basolateral side and the V1a receptor (V1aR) is distributed on the luminal side of the collecting ducts. Previously, we reported an increase of V1aR mRNA and a decrease of V2R mRNA in the collec...
متن کاملEnhancement of coronary vasodilator action of adenosine triphosphate by dipyridamole.
It has been reported that previously administered dipyridamole intensifies the coronary vasodilator action of adenosine compounds. In the present study, a combination of dipyridamole and ATP at doses that alone are ineffective was examined for its effect on the coronary sinus blood flow. In 10 anesthetized dogs, heart rate, arterial blood pressure, cardiac output, and coronary sinus blood flow ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2008
ISSN: 0007-1188
DOI: 10.1038/bjp.2008.10